Recent research has revealed that plasma cells in bone marrow exhibit unique general transcription mechanisms that are involved in cell death and renewal of healthy cells. The NIH has published the need of mature bone marrow plasma cells to affect gene expression in human health.
When we find gene disruption in human B cells we can activate protein secreting plasma cells to repair the protein deficient diseases. By activating the plasma cells, it causes cell death for the virus, infection , etc. by repairing the replication of the disease and allowing B cells the proteins needed to heal the presenting protein deficient immune issue.